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How to easily visualize groups’ classification?
The Wise son: I’ve created the best score to classify between two groups. We already talked about ROC and AUC to evaluate a diagnostic tool,…
What is Non-Inferiority (NI) all about?
The Wise son: In clinical trials, it is not always about demonstrating that the new product (or test, or treatment) is superior. Sometimes it is…
What to consider when calculating sample size for non-inferiority (NI) study?
The Wise son: In the previous post, we discussed non-inferiority (NI) study design. The first thing you need for establishing sample size for NI study,…
Why did the four sons leave the Haggadah and started IntegriStat's blog?
"To understand God's thoughts we must study statistics, for these are the measure of His purpose." — Florence Nightingale The Wise son: As you all…
What is IntegriStat all about?
The Wise son: IntegriStat is our safe place in this crazy world! Here we can rest, breath and analyze any data-set which enters our door.…
How to draw unadjusted and adjusted survival curves in R?
The Wise son: Survival analysis is one of the most common analyses in the medical world. Data is usually time-to-event, and many studies’ questions are…
How to appoint the national statistician?
The Wise son: The national statistician is the head of the Central Bureau of Statistics (CBS). The CBS performs statistical analysis about the state and…
ROCs’ best cut-off point for a diagnostic test
The Wise son: As Wicked said in our previous post, ROC curve can help find the best cut-off point of a diagnostic test; a cut-off…
ROC: Beyond Sensitivity and Specificity?
The Wise son: We already explained the importance of accuracy measures in evaluation of a diagnostic test. See here. The key measures we have described…
Sensitivity or specificity? And how to evaluate a test?
The Wise son: One may find this topic as confusing, and indeed it is very confusing!The goal of a diagnostic test is to define whether…
When to use a trend test?
The Wise son: Aren’t we all just trying to find trends everywhere? I hope you all have a positive trend in your life. A trend…
How can I obtain sample size in multiple regression?
The Wise son: I’m glad to see that you are taking a further step into sample size understanding. Obtaining a sample size and power analysis…
What should I consider when deciding on sample size?
The Wise son: This is definitely an important issue for research since it forces you to think about your study design. I call the sample…
Cox Regression, why can’t I just use logistic regression for survival data?
The Wise son: Oh, how I love to talk about Cox Proportional Hazard (PH) regression versus Logistic Regression. So, you see, it depends on the…
What is the key difference between Machine Learning (ML) and Statistical Modeling (SM)?
The Wise son: This is a very interesting discussion. There are many differences between the two, but in my opinion, the most important one regards…
What is this blog about?
Hello, I’m the Wise son, nice to meet you all. We are the four sons from the Jewish Passover Haggadah. We all love statistical discussions,…